Het lelijkste land ter wereld.

Spiegelbeeld der Wetenschap. Het Genootschap ter Bevordering van Natuur-, Genees- en Heelkunde 1790–1990

The remaining essays were all newly commissioned. Gerald Izenberg provides a balanced and readable account of the abandonment of the seduction theory (taking into consideration the newest discussions on this topic). Clark Glymour's piece reflects on Freud's relationship to nineteenth-century philosophy (including Franz Brentano) and neurology in terms of Freud's understanding of the mechanism o...

What is L TER ?

The LONG TERM ECOLOGICAL RESEARCH program (L TEA) is a network of field sites used to study structure and process in natural landscapes at temporal and spatial scales of decades or centuries. The ten sites now funded by the National Science Foundation's Division of Biotic Systems and Resources, include forest, prairie, desert, and aquatic environments. Major questions are addressed at each site...

39-47_0408PP_aan het Rot_CME.indd

Conventional pharmacologic treatments for major depressive disorder (MDD) generally take several weeks to several months to have a clinically meaningful effect. This time lag to response constitutes a major burden for patients and contributes to increased morbidity and mortality. Two published studies in patients with MDD have now provided evidence for rapid and robust antidepressant efficacy o...

Parameter Estimation for Bomhuet ter /Ferguson

The Bomhuetter/Fergnason loss reserving method consists of selecting a development pattern and, for each accident year, an initial ultimate loss ratio. From these, the reserve estimate is derived. In this paper, the usual way to obtain the development pattern from the cl~in ladder link ratios is criticized because it assumes a multiplicat~ve connection between past and future loss amounts where...

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